Study: Loss of smell in COVID-19 far more common than thought

Loss of smell is common in COVID-19, but fewer people say they have this symptom than objective tests reveal, a new study finds.

In fact, about 77% of COVID-19 patients who were directly measured had smell loss, but only 44% said they did, researchers found.

Direct measures of smell involve having patients smell and report on actual odors, while self-reporting includes getting data through patient questionnaires, interviews or electronic health records, the study authors explained.

“Objective measures are a more sensitive method to identify smell loss related to COVID-19,” said study co-author Mackenzie Hannum, a postdoctoral fellow at Monell Chemical Senses Center in Philadelphia.

Subjective measures, “while expedient during the early stages of the pandemic, underestimate the true prevalence of smell loss,” said Vicente Ramirez, a doctoral student at the University of California, Merced, and summer intern at Monell.

The research suggests subjective measures underestimate the true extent of smell loss and that it may be an effective tool for diagnosing COVID-19 early, the authors said in a Monell news release.

For the study, the researchers reviewed previously published studies on COVID-19 and loss of smell.

Their findings were published online recently in the journal Chemical Senses.

Senior author Danielle Reed, associate director at Monell, suggested that “measuring people for smell loss may become as routine as measuring body temperature for fever.”

More information

For more on COVID-19, head to the U.S. Centers for Disease Control and Prevention.

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Fading Sense of Smell Could Signal Higher Death Risk in Older Adults | Health News

By Cara Roberts Murez
HealthDay Reporter

(HealthDay)

MONDAY, Oct. 26, 2020 (HealthDay News) — If you’re a senior who can’t smell onions, smoke, chocolate or natural gas, it’s time to see your doctor.

Seniors who lose their sense of smell — which doctors call olfactory dysfunction — have higher odds of dying from all causes within five years, new research shows. Scientists had previously found a link between olfactory dysfunction and impaired thinking and memory.

“We suspected there would be an association with olfactory dysfunction and mortality as well, considering that this is an early marker for a lot of neurodegenerative diseases, including Parkinson’s and dementia,” said study author Dr. Janet Choi, a resident in otolaryngology at the University of Southern California.

Her team reviewed nationwide survey and death data from about 3,500 people age 40 and over. The surveys included self-reported loss of smell as well an objective smell test.

Over the five-year study, researchers found no increased risk of death based on self-reported loss of smell.

But the risk of death rose 18% for every 1-point decrease in scores on a “pocket smell test.” On the test, participants were asked to identify eight scents: onion, soap, leather, smoke, grape, strawberry, chocolate and natural gas. They needed to identify at least six to be considered having a normal sense of smell.

The mortality link was significant for adults 65 and older, but not among those between 40 and 64, researchers reported.

Sense of smell is mostly controlled by a nerve from the brain called the olfactory nerve. Olfactory dysfunction leads to more than 200,000 doctor visits a year, according to the study.

A diminished or lost sense of smell can lead to malnutrition, because people may lose their appetite or enjoyment of food, according to the researchers. It’s also linked to depression and a poorer quality of life.

The findings were published Oct. 22 in JAMA Otolaryngology-Head and Neck Surgery.

“We do know that, speaking to patients, they do lose their ability to enjoy life’s simple pleasures, like smelling flowers or enjoying a nice meal out with family or friends,” said Dr. Aria Jafari, an assistant professor of otolaryngology-head and neck surgery at the University of Washington in Seattle.

“Those things can severely impact their quality of life and that can result in depression and associated conditions that could result in a medical condition or death,” said Jafari, who wasn’t part of the study.

Loss of smell may also prevent someone from noticing the smell from a gas leak or a fire, which can be life-threatening. It can also be an early sign of Parkinson’s disease and Alzheimer’s. New loss of smell and taste can be a symptom of COVID-19.

Jafari said he screens patients for loss of smell and advises patients with olfactory dysfunction that they could be at a higher risk of injury.

Treatment varies depending on the reasons for the loss of smell, Jafari said. In some cases, treating chronic sinus issues could fix the

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