Two Rivers’ Maggie Klinkner aims to be a pediatric dentist

Name: Maggie Klinkner

Parents: Tim and Sam Klinkner

School: Two Rivers High School

Grade: Senior

GPA: 3.67

What extracurricular activities have you been involved with during high school? Throughout high school, I have been involved in student government, Junior Leadership through The Chamber of Manitowoc County, Boomerang, Fact, National Honor Society, Lights Leaders, Advisory Recreational Board, server at St. Peter the Fisherman, figure skating through the Manitowoc County Figure Skating Club, cross country, and track and field.

What is one academic accomplishment about which you feel particularly good? Being able to be involved in so many different things while still keeping up with all my school work. 

Which class or extracurricular activity influenced your decision regarding the career you plan to pursue? My chemistry, physics and advanced chemistry classes. Throughout middle school, science was never a class I really enjoyed, but my views changed when I entered these high school classes. My teacher had a large part in my choice, as she knew how to make the material we learned enjoyable and easy to learn. 

What advice do you have for those just starting their high school career? Don’t take anything for granted; go to that basketball game, go to that musical. High school is only four years long — make the best of it while you are still there. 

What are your plans after high school? I plan to attend Marquette University, where I will major in chemistry. After graduation, I would like to go to dental school and become a pediatric dentist.

What would you like to be doing 10

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Inspired by Her Cancer Struggle, Kan. Teacher’s Class Brings Holiday Cheer to Pediatric Patients

Inspired by Her Cancer Struggle, Kan. Teacher’s Class Brings Holiday Cheer to Pediatric Patients

Angela Holtgraves’ special education students began the Stocking Project in 2017 upon learning of Holtgraves’ own cancer battle

When the holiday season rolls around, hundreds of pediatric cancer patients in Kansas will receive stockings stuffed with toys — and it’s all thanks to teacher Angela Holtgraves and her students.

Holtgraves, 34, is a special education teacher, and for the last three years, has spearheaded a special initiative called Stocking Project with her students to spread goodwill and holiday cheer to those who need it most.

“It’s a nice way for us to help others,” she tells PEOPLE in this week’s issue. “This is their way of being able to show the world, ‘I might have a disability, but I can still do some pretty incredible things.’”

For Holtgraves, a mom of two based in Olathe, cheering up young oncology patients at Kansas City’s Children’s Mercy Hospital is personal; she overcame a breast cancer diagnosis at 28, and one of her students was a leukemia survivor. Sharon Houser, the teacher with whom she started the Stocking Project, also has a daughter who is a young breast cancer survivor.

Holtgraves’ students at Shawnee Mission North High School had previously done projects to give back — including making hygiene bags for homeless people — but when they learned of her history with cancer in 2017, switched gears to refocus their efforts.

Courtesy Angela Holtgraves Angela Holtgraves

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Together, they came up with the Stocking Project, which went with Holtgraves when she began teaching at Olathe West High School in 2018.

The group’s initial goal that first year was to create 20 stockings. Instead, they filled 75 in just two weeks, a number that has continued to grow each year for a total of nearly 600.

PEOPLE’s second annual Kindness Issue is dedicated to highlighting the ways, big and small, that kindness can make a difference and change lives. Click here and pick up the issue, on stands Friday, Oct. 30, for more stories on the impact of kindness from Priyanka Chopra Jonas, Sterling K. Brown, Heather Locklear and other stars, as well as everyday people practicing kindness in their communities. To share the story of someone who’s done something exceptionally kind, email [email protected]

Holtgraves estimates that she and her students have raised more than $50,000 in donated goods, helped along with gifts from companies like Russell Stover and Sephora, as well as local businesses.

“The sense of pride they get is everything,” she says.

Angela Holtgraves’ students

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Each year, Holtgraves typically dedicates a day in December to filling the stockings, which are broken down by age group and sex, including male, female and gender-neutral patients, with about 20 items each.

Because of COVID-19, however, this year’s plan

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Taysha Gene Therapies Receives Rare Pediatric Disease Designation and Orphan Drug Designation for TSHA-104 to Treat SURF1-Associated Leigh Syndrome

Taysha anticipated to submit Investigational New Drug Application for TSHA-104 to FDA in 2021

Rare pediatric disease and orphan drug designations now obtained in multiple pipeline programs, including TSHA-101 for GM2 gangliosidosis, TSHA-102 for Rett syndrome and TSHA-118 for CLN1

Taysha Gene Therapies Inc. (Nasdaq: TSHA), a patient-centric gene therapy company focused on developing and commercializing AAV-based gene therapies for the treatment of monogenic diseases of the central nervous system in both rare and large patient populations, today announced that it has received rare pediatric disease designation and orphan drug designation from the U.S. Food and Drug Administration (FDA) for TSHA-104, an AAV9-based gene therapy in development for SURF1-associated Leigh syndrome. Taysha anticipates it will submit an Investigational New Drug (IND) application to the FDA for TSHA-104 in 2021.

“We have now obtained rare pediatric disease and orphan drug designations in multiple gene therapy programs, which we believe will allow us to work more effectively with the FDA as we advance our broad portfolio,” said RA Session II, President, CEO and Founder of Taysha. “The receipt of these designations highlights the dedication that our team has to advancing our gene therapy pipeline as efficiently and rapidly as possible.”

Leigh syndrome is a severe neurological disorder that usually presents in the first year of life. It is characterized by progressive loss of mental and movement abilities that can result in death within two to three years. Approximately 10-15% of people with Leigh syndrome have a SURF1 mutation.

“Being diagnosed with a mutation in the SURF1 gene is a truly devastating event for families,” said Kasey Woleben, Founder of Cure SURF1 Foundation. “Taysha’s commitment to developing a gene therapy for SURF1 deficiency is greatly welcomed by the patient community and has the potential to save the lives of children afflicted with this progressive disorder.”

Taysha has secured rare pediatric disease designation and orphan drug designation for multiple of its programs, including GM2 gangliosidosis, CLN1, Rett syndrome and now SURF1. In addition to these designations, the company also has fast track status for the CLN1 program.

“SURF1 deficiency is a monogenic mitochondrial disorder and is the most common cause of cytochrome c oxidase deficient Leigh syndrome,” said Steven Gray, Ph.D., Chief Scientific Advisor of Taysha and Associate Professor in the Department of Pediatrics at UT Southwestern. “Obtaining these key designations highlights our commitment to developing a gene therapy for the treatment of SURF1 deficiency.”

The FDA defines a rare pediatric disease as a serious or life-threatening disease in which the disease manifestations primarily affect individuals aged from birth to 18 years. Pediatric diseases recognized as “rare” affect under 200,000 people in the U.S. The Rare Pediatric Disease Priority Review Voucher Program is intended to address the challenges that drug companies face when developing treatments for these unique patient populations. Under this program, companies are eligible to receive a priority review voucher following approval of a product with rare pediatric disease designation if the marketing application submitted for the product satisfies certain

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Pediatric mental health screenings increasing, but need remains

The number of behavioral health screenings for children are increasing year-over-year, but experts said more can be done to catch mental health conditions early on, especially as they pose more of a risk to children during the COVID-19 pandemic.

According to data from the Connecticut Department of Social Services, behavioral health screenings billed to Medicaid for children aged four to 17 went up by 50,000 from 3,697 in 2013 to 53,756 in 2019. Similar screenings for children under the age of three went up from 27,992 to 73,262.

“I wish I could say it’s because of educating practices but the bottom line is those numbers are increasing as time goes on and more resources become available,” said Dr. David Krol, a pediatrician who is also vice president for health initiatives for the Child Health and Development Institute of Connecticut. “We’re seeing more pediatricians doing these screenings.”

Valerie Lepoutre, statewide peer recovery program manager for the National Alliance on Mental Illness’ Connecticut chapter, said screenings and loved ones keeping an eye out for mental illness in children is even more crucial as many experience new levels of stress given the COVID-19 pandemic.

“We’re constantly…saying to keep an eye out to how your child is responding and acting during this time and not dismiss it,” Lepoutre said. “We don’t know what the long-term effects will be and it could lead to other mental health challenges. Even if it goes away, it’s better to get help now.”

While behavioral health screenings and mental illness awareness are increasing, the American Academy of Pediatrics reported in a 2017 study that up to 20 percent of children experience a mental health disorder and many remain untreated. Lepoutre said that it can take up to a year for some mental illnesses to be diagnosed.

These delays are costly, not only in setting out a treatment plan, but for a patient’s physical health. Lepoutre said delays in diagnosis can lead to many patients not getting help for their mental illness until their 20s at which point many young adults are on their own insurance and may struggle with finding the time to navigate the behavioral health care system and to find a care team. Mental health can also take a toll on physical health, particularly if a child experiences trauma at a young age.

“This could cause other challenges for our generation ahead of us to see how are they physically handling the stress,” Lepoutre said. “Children are resilient but that post-traumatic growth is huge. We have to be mindful of negative consequences and effects this can have later in their lives.”

But there’s a number of ways experts are working to improve early detection. NAMI hosts educational programs, including one called “Ending the Silence” which is designed to teach teens the signs of mental illness.

Lepoutre said that many pediatricians only see patients once a year for wellness visits. This means it’s important to educate family, teachers and students of the signs of mental illness since they’re

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What Qualities Set a Good Pediatric Dentist Apart From the Rest?

No pediatric dentist worth their salt will paint a weak picture of themselves. If you listen to them advertise their services, you will be at a loss when it comes to choice. Everybody looks great on paper or the digital display and they sound awesome in the media outlets.

You may need to have personal experience with a few to see who stands up to the image they have created of themselves. Some pediatric dentists may have opted for pediatric dentistry because they saw a niche. Others have genuine love and regard for children and want to make their dental experience as trauma-free as possible.

In your search for the perfect dentist for your child or children, make sure they have the following qualities:

He / she should have the child's wellbeing at heart

Everything from attitude to the environment in the office should be geared towards creating an ambiance that favors children. It is not just about toys and Sponge Bob playing on TV. Children should find comfort and something to keep them occupied and entertained in the dentist's office. The staff should be able to interact with the little ones at their level so that they feel at ease.

The décor of the exam room, the smells and sounds should make the child feel comfortable rather having that clinic atmosphere that only makes a child feel the tension.

The supplies should be kiddie-sized

You cannot use the same gadgets that are used on adults for children. They are little and therefore have little mouths. Imagine trying to use equipment meant for adults on a child. Not only will she resist it, for obvious reasons, but she will also be traumatized by the whole process. A pediatric dentist must have the child's comfort at heart even when purchasing supplies and equipment for their office and exam room.

Converse with the child at their level

No, you do not need to sound like Minnie Mouse. Of course, your tone and pitch should be appropriate, but it is more like using words that the child understands. So, even as you work on your delivery, dental lingua is only going to earn you blank confused looks.

Also, remember all those gadgets don't exactly look like the utensils they use to eat pies. It is bound to look a tad intimidating. It would help if you would gently explain what any gadget you have to use it for and how it is going to help the child.

No two children are the same, so a good dentist first gets a feel of each little patient before they talk to them by having a chat with the parents of new patients to know whether or not kiddie talk will work or the child will not buy it .

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Visiting a Pediatric Dentist Is Essential to Keeping Your Child's Teeth Healthy

Keeping a child's teeth clean (even baby teeth) is vital to improving his or her overall health and ensuring proper growth and development. Encouraging healthy habits, such as regular brushing and flossing, as well as proper nutrition, will go a long way in keeping a child's teeth healthy. Beyond day-to-day care, scheduling regular visits to a pediatric dentist is essential in preventing infection, disease, and identifying any potential problems in a child's mouth. Following these three essential steps will help to keep a child's teeth healthy.

1. Regular Brushing and Flossing

For adults, regular brushing and flossing might seem like a no-brainer, but for many kids, brushing and flossing can seem like a chore that they would rather avoid. To help introduce a child to regular brushing, it is best to start when he or she is two years old. Early on, take care to only use a small amount of toothpaste (about an eighth of what an adult would typically use). As many young children will swallow toothpaste and not spit it out, it's best to use a fluoride-free toothpaste until a child is old enough to stop swallowing it. At some point, kids will want to brush their own teeth – it's okay to let them, but be sure to give their teeth an extra brush once they've had their turn. Most children won't get into the habit of regularly giving their teeth a proper brush until age 8 or 9.

It is best to start to start flossing between a child's teeth as soon as his or her teeth touch each other. Floss once a day or as needed with either regular string floss or plastic floss picks. Eventually, repeated proper instruction will enable kids to start flossing on their own. Let them try a few times under supervision, and be sure to reward them for a job well done to encourage continued thorough flossing.

2. Proper Nutrition

Maintaining proper nutrition for a child is vital in keeping his or her teeth healthy and preventing decay. Frequent snacking of unhealthy foods can increase a child's risk of tooth decay. Foods high in sugar can cause cavities if they are left on a child's teeth for too long. Bacteria eat the sugar left on teeth and create acid, which dissolves enamel. To avoid this, try to limit a child's intake of sugar-high foods and lengthen the intervals between snacks.

3. Routine Visits to A Pediatric Dentist

In order to ensure that a child's teeth remain healthy and develop properly, it is essential to schedule routine visits to a trusted pediatric dentist. Pediatric dental professionals can find and treat early signs and symptoms of infection and structural abnormalities and can provide parents with further information on proper tooth care for their children. Pediatric dental professionals can also provide information and advice on early orthodontics as needed.

Following these three steps will ensure your children are on the right track for proper oral health.

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Choosing a Pediatric Dentistry

A pediatric dentist is a dentist that takes care of children from infancy through their teen years when at that time they will switch to a regular dentist. Pediatric dentistry is a specialty that a dentist can choose to specialize in after becoming a licensed dentist. They have to have completed four years of dental school and two more years of residency training in dentistry for infants to teens that have special needs.

Some of the treatments that a pediatric dentistry office might offer can include:

• Oral health exams for infants

• Prevention dental care that includes fluoride treatments, cleanings and diet and nutrient information.

• Counseling for habits such as thumb sucking and pacifier use

• Treatment and early assessment for improper biting correction and teeth straightening

• Repairing defects or tooth cavities

When you are looking for a pediatric dentistry for the first time there are some things that you should look for before you make your choice. To find a good pediatric dentistry you could ask friends and family for a recommendation or you could ask your child’s pediatrician.

• Find a pediatric dentist who is a member of the American Academy of Pediatrics, American Academy of Pediatric Dentistry, or American Dental Association.

• To help you located dental clinics in your area you can use the search tool of American Academy of Pediatric Dentistry

• Find a pediatric dentist that will make the dental experience for your child as comfortable as possible, especially if the child is young and this is the first experience visiting a dentist

• When you find a pediatric dentistry schedule a consultation with the dentist before setting an appointment for your child

• During your consultation look around the waiting room and the exam rooms to make an assessment about the ambiance. Is it child friendly? Are there child-sized furniture in the waiting area and does it have a play area?

• Children do get bored easily, especially the younger ones so is there a television where they can watch cartoons. Are there toys, coloring books, etc? The needs of children of all ages should be evident.

• When the child sees a dentist for the first time make sure that the dentist interacts with your child and how your child responds to the dentist and dental assistants. If the child is scared or crying, how do they act?

• Is the parent allowed to go back with the child until the child feels comfortable going on their own.

These are just some of the many things you should look for before selecting a pediatric dentistry.

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The Functions Of A Pediatric Dentist

A “pediatric dentist” is a specially trained dentist who provides services to children. Generally, “children” is defined as people under the age of 14, but with regards to pediatric dentistry we are generally talking about toddlers. A pediatric dentist undergoes specialized training in the aspects of both primary and secondary teeth, and the challenges that are faced in both cases. Additionally, a pediatric dentist is trained in child psychology, which assists them in performing the tasks necessary on a patient who is both afraid and unwilling to have their teeth and mouth examined.

The duties of a pediatric dentist involve assessing the state of oral health of the patient through an examination, as well as the correction of any problems through treatment. This may involve the filling of cavities which can be a scary and painful experience for children, necessitating the child psychology aspects of the dentist’s training.

The dentist must understand how to keep the child calm and still long enough to perform the procedure that is necessary in order to restore the state of oral health to the patient. The child does not understand why they are being subjected to this pain, and is not able to be reasoned with like an adult. The protocols that are followed are derived from study of childhood mentalities and how to overcome the reactions that are natural for children.

Another aspect of pediatric dentistry is the education of parents on the oral health of their children. As an example, many parents will fail to brush their child’s teeth due to the difficulties of doing so, combined with the belief that if the child is not eating candy or sweets that they do not need to brush. In reality, there is a tremendous amount of sugar in milk, and primary teeth are prone to cavities and infections as a result of a lack of care. If the oral care is lax, cavities can form which must be assessed as far as the severity to see if they will cause pain before falling out or if they must be filled. A pediatric dentist is trained to help parents understand the need for oral care in children, and how to accomplish it.

If you have a child, makes sure that the dentist you choose is a pediatric dentist in order to assure that they get the best care possible. It only takes a second to ask.

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Why Search for a Pediatric Dentist of Great Reputation

Seeing your child get bullied just because of a broken piece of tooth is something that you don’t like to happen. Taking care of your kid’s dental needs is one way of showing how much you care. Your concern about his/her overall health can start from bringing him/her to your family dentist. Dentists that are expert in handling children’s dental cases are called pediatric dentist. Dealing with your child’s early dental issues is a precautionary action to prevent further dental problems in the future. Of course, choosing the right dentist for your child is a vital step to take.

So, what should you seek out for a children’s dentist? First and foremost is the professional qualification of the dentist. Does he/she receive the compulsory academic course and undertake associated lab and intern training? These are fundamental part of acquiring a medical degree in dentistry. After earning such requirement, the dentist must have continued his/her course for post-graduate studies for field of specialization like pediatric dentistry. Of course, the school must have been accredited by the American Dental Association. Once your kid’s dentist was educated from sedation dentistry and child behavior, these are good signs of dedication.

After graduation and accreditation, this dedication will be manifested further as the pediatric dentist continues to educate himself/herself by broadening his/her knowledge, techniques, and skills in pediatric dentistry through researches, seminars, and workshops. Children’s dentistry is an area of dentistry that requires constant learning and advancement so as to adapt with the present children’s behaviors and current technologies. A good dentist, who strives upgrading himself/herself to carry on his/her dental practices with great satisfaction, proving himself/herself with certificates, is someone who really cares about the overall health of his/her patients.

You can also determine that the dentist is committed to providing the best dental care possible through certificates of recognition he/she received from his/her professional colleagues and affiliations. The American Academy of Pediatric Dentistry usually recognizes the efforts of every dentist who are dedicated to excellence in pediatric dentistry. There are dental organizations and philanthropic foundations that give awards to dedicated dentists as well.

Of course, a pediatric dentist of good reputation is not measured by his/her medical degrees and papers of recognition or awards he/she received. Although these pieces of papers are evidence that he/she is a qualified dentist, what really matter most is his/her excellent reputation and genuine care towards his/her patients. Since it is normal for children to feel uneasy when visiting dental clinics, the dentist must therefore be capable of displaying amiable qualities like being friendly, compassionate, gentle, and accommodating. These qualities are important in winning the trust of the child. And earning the child’s trust is a key to successful dental diagnosis and treatment. Well, these are the important things to consider before having your kid’s dentist.

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Who Is a Pediatric Dentist and What Do They Do?

A dentist, in the simplest of terms, is a tooth doctor. A pediatric dentist is a tooth doctor who specializes in treating children’s teeth. You have probably heard some harrowing tales stemming from visits to the dentist. Well, you would be forgiven for being apprehensive, but honestly, go with an open mind.

A pediatric dentist takes care of children’s teeth from infancy to the teenage years. They are trained to not only take care of children’s teeth, gums and mouth; they are also trained to handle children as they handle the treatment.

Baby teeth

· The first set of teeth show up in the first 6 months of life.

· Then they begin to lose them from the age of 6. It would seem 6 is the lucky (… or unlucky) number where children and teeth are concerned.

· The baby teeth, as they are commonly known, are then replaced by permanent teeth. Secondary (permanent) teeth come with their own set of issues and if they are not taken care of properly, oral decay and disease may be constant companions. If you have ever suffered a toothache, you know you do not want that. The pain is beyond horrible.

· Childhood dental caries is an infectious disease that is very common in children. Pediatric dentists are equipped to handle such issues competently and calmly. Calm is of utmost importance in a pediatric dentist’s office.

Training

Training for pediatric dentists includes:

  • Four years of dental school
  • Two years of residency training in pediatrics. This includes dentistry for infants, children, teens, and children with special needs.

Type of treatments provided by pediatric dentists

They handle all manner of healthcare and maintenance to do with children’s and teenagers’ teeth. These include the following:

· Habit counseling – This has to do with habits that affect the teeth, like the use of pacifiers and thumb sucking.

· Risk assessment – Oral health checks for infants to assess risk for caries in both the child and the mother

· Orthodontics – Teeth alignment and bite checks

· Preventive care – Cleaning and fluoride treatment, and nutritional advice

· Repair – Tooth defects and cavities

· Management – Conditions like mouth ulcers, mucoceles, and periodontal disease, frenula, and gum diseases

· Diagnosis – Oral conditions that arise from complications brought about by ailments and conditions like asthma, diabetes, hay fever, ADHD as well as congenital heart defects

· Dental care – Especially for dental injuries like knocked out, fractured and displaced teeth

A pediatric dentist offers expertise in children’s dental care and is endowed with skills to ensure that the dental experience for the child does not turn out to be a traumatizing experience that fills them with trepidation at the mention of the dental clinic

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