Illinois institutes COVID-19 restrictions in all 11 regions as U.S. reports 81K new cases

Nov. 1 (UPI) — U.S. COVID-19 cases spiked in the Midwest on Sunday as current and former health officials warned that Thanksgiving gatherings could further increase the spread of the virus.

The United States reported 81,227 new cases and 862 new deaths bringing its world-leading totals to 9,189,715 infections and 230,870 fatalities, according to data collected by Johns Hopkins University.

All 11 regions in Illinois will be placed under resurgence mitigations including prohibiting indoor dining and bar service, closing outdoor dining at 11 p.m. and limiting gatherings to 25 people or less beginning on Wednesday as Region 2 recorded an average positivity rate above 8% for three consecutive days.

“As cases, hospitalizations and deaths are rising across our state, across the Midwest and across the nation, we have to act responsibly and collectively to protect the people we love,” Illinois Gov. J.B. Pritzker said.

Illinois recently reported three consecutive record-breaking case days including 7,899 new infections on Saturday.

The state broke the streak on Sunday as it reported 6,980 new cases and 35 additional deaths, bringing the state’s total to 417,280 infections and a death toll of 9,792, according to the Illinois Department of Public Health.

A surge in hospitalizations has also been reported in the region as Ohio recorded 1,629 hospitalizations as of Friday — the state’s highest number since the pandemic began in March.

Dr. Anthony Fauci, the director of the National Institute of Allergy and Infectious Diseases and a member of the White House’s coronavirus taskforce, drew heat from the White House on Sunday as he contradicted President Donald Trump’s message that the United States is “rounding the turn” on the virus, warning the country is primed to experience “a whole lot of hurt” as winter approaches.

Dr. Scott Gottlieb, who served as commissioner of the Food and Drug Administration under the Obama administration, said “things are getting worse around the country” citing 23 states that are accelerating the spread of the virus and 15 states reporting a positivity rate above 15%.

“I think Thanksgiving is really going to be an inflection point. I think December is probably going to be our toughest month,” Gottlieb told CBS News’ Face the Nation.

Gottlieb said, however, he doesn’t believe the United States will reinstate widespread lockdowns as Europe has done in recent weeks.

“I don’t think the political support is here for that even at the state level. I think you’re going to see targeted mitigation. States take local actions, but we’re going to have to start taking more aggressive actions,” he said.

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Feinstein Institutes researchers find effective COVID-19 ‘cytokine storm’ treatment

Some immune systems have responded to coronavirus disease 2019 (COVID-19) infections by going into overdrive, resulting in an overzealous inflammatory response referred to as a cytokine storm. In a retrospective study of nearly 6,000 patients, researchers from The Feinstein Institutes for Medical Research and Northwell COVID-19 Research Consortium have identified the most effective immunomodulatory therapies to treat patients with evidence of this cytokine storm and improve patient survival.

This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20201020006139/en/

Dr. Negin Hajizadeh and colleagues. (Credit: Feinstein Institutes for Medical Research)

A multidisciplinary team of investigators, led by Negin Hajizadeh, MD, a pulmonary and critical care physician, and associate professor at the Feinstein Institutes, analyzed the electronic health records of hospitalized COVID-19 patients across 12 of Northwell Health hospitals – New York State’s largest health system – between March 1 and April 24, 2020. The results were published today in CHEST, by Sonali Narain, MD, assistant professor at the Feinstein Institutes, corresponding author, and team.

Patients were divided into one of six groups; no immunomodulatory treatment (standard of care), patients who received intravenous corticosteroids, anti-interleukin 6 antibody therapy (tocilizumab) or anti-interleukin-1 therapy (anakinra) alone or in combination with corticosteroids.

The results show that the most effective treatment was the combination of corticosteroids – such as dexamethasone – with tocilizumab when compared to standard of care. Additionally, there was an improvement if corticosteroids were used alone, or in combination with tocilizumab or anakinra when compared with standard of care.

“Cytokine storms are a hallmark for many COVID-19 patients and are associated with the most severe form of this illness,” said Dr. Hajizadeh, associate professor at the Zucker School of Medicine at Hofstra/Northwell and co-senior author on the paper. “Our findings suggest that with the intervention of certain drugs like corticosteroids, we can battle the cytokine storm and improve outcomes to the point that we believe we have found a new standard of care for seriously ill patients.”

Overall, there were twice as many males as females in the cohorts, and more than 65 percent had never smoked. Contradictory to previous reports, the Black population was associated with better survival compared to white patients. Additionally, the most common comorbidities across the groups of patients that experienced a cytokine storm include:

  • Hypertension (44-59 percent);

  • Diabetes (32-46 percent);

  • Cardiovascular disease (5-14 percent);

  • Chronic kidney disease (5-12 percent);

  • Cancer (5-11 percent);

  • Asthma (3-12 percent).

“Dr. Hajizadeh’s major COVID-19 research study gives timely and crucial new knowledge about using currently available anti-inflammatory drugs,” said Kevin J. Tracey, MD, president and CEO of the Feinstein Institutes. “This information will help others save lives.”

The researchers hope that the findings are useful for frontline providers to care for severely ill COVID-19 patients and to aid in the future design of large randomized controlled clinical trials, the gold standard of medical research.

About the Feinstein Institutes

The Feinstein Institutes for Medical Research is the research arm of Northwell Health, the largest health care provider and private employer

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National Institutes Of Health (NIH)

Cabrini’s work is fundamentally about responding to local need to have which contains addressing issues of health, nutrition, education, and protection, as effectively as guaranteeing mental and spiritual well-becoming. About Weblog – The Division of Health and Human Solutions (HHS) is the United States government’s principal agency for protecting the health of all Americans and offering vital human services, particularly for these who are least able to aid themselves.

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Healthcare business is acknowledging that the disruption will come outside. But in the US, since the starting of the Trump regime, health care corruption seems to be acquiring worse, in the context of severely worsening corruption in the executive branch of government.

According to my Twitter list of health care policy authorities, the Big Undesirable President Trump will now sabotage” Obamacare so it fails spectacularly, proper just before the mid-term elections, dragging millions of poor people down with it. Sabotage, espionage, life is very good when you are kibitzing from the sidelines.

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