Carrot-based Japanese herbal medicine may improve muscle complications associated with COPD

Chronic obstructive pulmonary disease (COPD) is a lung disease caused by long-term inhalation of harmful gases such as cigarette smoke. Scientists have recognized deterioration of muscle tissue, known as, as a secondary effect of damaged lungs. This frailty makes it difficult for individuals to move around and exercise, which is turn worsens the state of their lungs, causing an endless downward spiral in overall health.

Exercise therapy is the only established treatment for the skeletal muscle complications of COPD, however, depending on the severity of sarcopenia frailty in the patient, such treatment may not be possible. This imbalance has become an urgent issue to address. Ninjin’yoeito is a carrot-based Japanese herbal medicine commonly given to people recovering from anorexia and physical weakness after illness or surgery for its supplementary effect in restoring physical strength. Also, the medicine has been seen to improve muscle mass loss in aging mice through the activation of PGC-1α- a protein involved in improving muscle function.

Based on this, we hypothesized that Ninjin’yoeito enhances PGC-1α expression in skeletal muscle and may improve muscle complications associated with COPD.”


Kazuhisa Asai, Associate Professor, Osaka City University Graduate School of Medicine

He led a research group in testing this hypothesis by including Ninjin’yoeito in the diet of mice who had been exposed to cigarette smoke for 12 weeks. Their findings were published online in the international scientific journal International Journal of Chronic Obstructive Pulmonary Disease on November 27, 2020.

Professor Asai’s team measured the lower leg muscle mass of the smoke-exposed group of mice with a microCT and noticed they had atrophied, like human COPD patients. However, he saw no such change in muscle mass with the experimental group of mice, suggesting that the addition of the carrot-rich medicine cancels out the effects of sarcopenia frailty.

“We believe that this is a useful finding and that Ninjin’yoeito may break the vicious circle of sarcopenia frailty in COPD patients”, adds Associate Professor Asai. “We would like to consider clinical trials in the future.”

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Journal reference:

Miyamoto, A., et al. (2020) Ninjin’yoeito Ameliorates Skeletal Muscle Complications in COPD Model Mice by Upregulating Peroxisome Proliferator-Activated Receptor γ Coactivator-1α Expression. International Journal of Chronic Obstructive Pulmonary Disease. doi.org/10.2147/COPD.S280401.

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NE China to open herbal medicine industrial park

(MENAFN) Northeast China’s Heilongjiang Province has exported an industrial park processing herbal medicines imported from Russia.

According to local officials, the industrial park in the Suifenhe sub-area of the Heilongjiang Pilot Free Trade Zone (FTZ) has seen the registration of six herbal medicine processing companies.

The park will have an annual medicine processing capacity of 165,000 tonnes, with an overall investment of 339 million yuan (about 51.46 million U.S. dollars),

A new policy allows herbal medicines, such as ginseng and licorice, from Russia to be processed in the Suifenhe area of the FTZ.

Imported drugs can be unloaded, primarily processed and sold directly in Suifenhe, thus helping companies reduce costs, said Wang Tengli, general manager of a local pharmaceutical trading company with an annual processing capacity of 2,000 tonnes.

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Medical groups clash over insurance coverage of herbal medicine


By Lee Hyo-jin

A pilot program rolled out by the government to include several types of herbal medicine in treatments covered by national health insurance was welcomed by practitioners of traditional Korean medicine. It, however, immediately provoked backlash from Western medical doctors.

As the government has plans to expand the coverage for more herbal medicine in the future following the progress of the trial program, the mixed reactions of the two medical groups may deepen into another dispute.

Under the pilot program, which started on Nov. 20, patients at traditional Korean medicine clinics who are prescribed treatments for menstrual pain, facial paralysis, or the aftereffects of cerebrovascular diseases, pay only half of the fee for the herbal medicine, as the rest is covered by state insurance.

The three-year test run is aimed at reducing the financial burden of patients and establishing a verified system to ensure the safety and effectiveness of herbal medicine, according to the Ministry of Health and Welfare.

Around 8,700 clinics providing traditional Korean medicine treatments across the country ― approximately 62 percent of the total ― have agreed to participate in the program.

Why Western medical doctors oppose

The announcement was immediately met with strong backlash from the Korea Medical Association (KMA), the largest Western medical doctors’ group in the country with more than 130,000 members. The association strongly condemned the government’s decision through a press release, calling it a “nationwide clinical trial using unverified medicine.”

They argued that easing public access to traditional Korean medicine and related herbal therapy will pose a risk to people’s health as they claim the safety of the treatments have not been adequately verified and there is no scientific evidence for their efficacy.

The association also pointed out that the program may lead to poor quality of herbal medicine, due to a shortage of certified herbal medication dispensaries and lenient control over them. While most small traditional Korean medicine clinics have own dispensaries, some large ones have outside dispensaries make the medicine.

“There are only five outside herbal medication dispensaries in the country certified by the government. This means that those five facilities will be preparing all the herbal medicines for over 8,700 clinics during the pilot program period,” KMA member Kim Gyo-woong said at a press conference, Nov. 23.

“The mass production system may lead to failure in quality control and safety issues, and considering the current lax control over dispensaries, the system may lead to illicit manufacturing of drugs,” he added.

In addition, the KMA stressed that the health authorities should focus more on the unresolved issues surrounding the side effects of traditional medicine.

More than half of medical disputes reported in relation to traditional medicine treatments were about herbal medicine, followed by Chuna manual therapy, acupuncture, and skin care, the association said, citing recent data from the Korea Consumer Agency.

“The government must immediately retract the policy which only puts public safety at risk, and launch a full investigation on all herbal dispensaries and prohibit the operation

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A review of Traditional Chinese herbal medicine in management of COVID-19

The COVID-19 pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected over 59.65 million people worldwide and claimed the lives of over 1.4 million. The virus, first detected in late December 2019 in Wuhan, China, is the most significant public health problem since the 1918 Spanish flu pandemic. There are no effective and safe drugs that can be used to treat COVID-19 disease nor vaccine to prevent SARS-CoV-2 infection. Since the first cases were detected in Wuhan, several traditional Chinese herbal medicines have been used to treat this infection.

Now researchers led by David Lee from Bio-Organic and Natural Research Laboratory, McLean Hospital, Harvard Medical School, Belmont have summarized the experiences with the use of traditional Chinese herbal medicines for the management of COVID-19. Their study titled, “Traditional Chinese herbal medicine at the forefront battle against COVID-19: Clinical experience and scientific basis,” was published in the January 2021 issue of the journal Phytomedicine.

Study: Traditional Chinese herbal medicine at the forefront battle against COVID-19: Clinical experience and scientific basis. Image Credit: Dragon Images / Shutterstock

Background

China has a rich history of traditional herbal medicines. Traditional Chinese herbal medicine (TCM) has been used for over 5,000 in over 300 epidemics that the nation has faced. When the COVID-19 pandemic emerged early this year, treatment with TCM was reported to have been used with over 90 percent efficacy.

Study particulars

This study was a systematic review of several traditional Chinese herbal medicines that were used in Wuhan,  looking at their efficacy in the management of COVID-19. At present, patients admitted to hospitals (except TCM hospitals) are primarily treated with western medicine as frontline treatment.

Principles of TCM use

The western medications used include antibiotics and painkillers. At present, over 100 herbal TCM formulae are available for use in epidemic related infections. Authors write, “TCM is now credited for the successful battle against COVID-19 in China”.

The ancient Chinese medical text Huangdi Neijing explains that 12 meridian lines run through the human body and help balance the immune system and provide good health. The lung meridian line interconnects with the large intestine functionally and controls the body fluid (water). The researchers write, “Expelling phlegm and relaxing the bowels with laxatives are common methods for treating lung diseases. Therefore, maintaining a smooth and open channel is an important function served by the lung meridian line.” Treatment of COVID-19 is basically to “expel the toxic moisture from the upper respiratory system and to improve intestinal obstruction.” They added that the TCM method of treatment tries to maintain the balance of the lung meridian system and to restore the lung and large intestine balance using acupuncture and herbal medicine.

Treatment of COVID-19 using TCM

TCM has been used as a first-line treatment for COVID-19 disease since the emergence of SARS-CoV-2. Qingfei Paidu decoction for example, has been used in a three-day course leading to an over 90 percent efficacy.

The team of researchers wrote, “The Chinese government announced that TCM is one of the recommended therapeutic options for the treatment of COVID-19 in the third version COVID-19 treatment guidelines, published on January

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Chinese herbal medicine launched in Philippines


Chinese herbal medicine launched in Philippines

Sheila Crisostomo (The Philippine Star) – November 25, 2020 – 12:00am

MANILA, Philippines — A Chinese herbal medicine designed to relieve influenza symptoms such as those of COVID-19 was officially launched in the Philippines on Monday.

According to Philippine Archipelago International Trading Corp. (PAITC) president Olivia Limpe-Aw, the Lianhua Qingwen capsule is the first traditional Chinese medicine registered by the Food and Drug Administration (FDA) under the “pharmacological category.”

“This a landmark registration? The COVID-19 pandemic has brought to fore the importance of TCM (traditional Chinese medicine) and, in particular, the significant role of Lianhua Qingwen in the treatment of COVID-19,” she noted in a webinar.

Aw added the medicine is now available at selected drugstores in the Philippines, but it will be accessible at more outlets soon.

She said the entry of Lianhua Qingwen in the country “will be a big help to our countrymen.”

AIf thereIs a silver lining to this COVID-19 pandemic, itss the awareness for traditional Chinese medicine and the provision for effective, safe and affordable treatment,s she maintained.

Approval

In August, the Chinese embassy in the Philippines had announced that the FDA had approved the application for registration of Lianhua Qingwen as a “traditional medicine.”

An embassy statement showed the product is manufactured by “one of China’s renowned Traditional Chinese Medicine manufacturers, Shijiazhuang Yiling Pharmaceutical Co. Ltd.”

In China, the Lianhua Qingwen capsule is an approved treatment for mild and moderate cases of COVID-19.

Based on Lianhua Qingwen’s certificate for product registration (CPR) issued by the FDA, the medicine “helps remove heat-toxin invasion of the lungs, including symptoms such as fever, aversion to cold, muscle soreness, stuffy and runny nose.”

The product can be procured in the Philippines with a doctor’s prescription.

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Global Herbal medicine market size to exceed USD 411 billion by 2026

The latest report on ‘herbal medicine market’ thoroughly scrutinizes this business space while providing qualitative insights, historical data, and verifiable projections for 2020-2026 to the companies that are operational in this industry.

Selbyville, Delaware, Oct. 29, 2020 (GLOBE NEWSWIRE) — According to the credible sources, global herbal medicine market is expected to reach a valuation of USD 411.2 billion by the year 2026. Increasing product adoption by the population across the world, rising support & funding from government for research & development of herbal medicines, and easy availability of the product are the major factors propelling the industry growth. Further, benefits such as low cost, and no side effects are also contributing to herbal medicine market outlook.

Global herbal medicine market report studies the landscape based on several segmentations, such as source type, distribution channel, category, form, and regional outlook. It enlists the factors that influence the segmental share along with their growth rate projections over the analysis timeframe. Furthermore, the document contains granular information about competitive landscape of the market defined by each participant, along with their business profile, product portfolio, and market stake.

Highlighting category

Estimates cites that herbal pharmaceuticals segment held a major share in global herbal medicine industry in 2019, owing to rising geriatric population, and high consumer awareness. Other factors like negligible side effects, supplier innovations, and launch of Current Good Manufacturing Practices (CGMP) by the FDA for dietary supplements are expected to drive the segmental growth.

Meanwhile, herbal beauty products segment is predicted to register robust growth rate during the forecast period, mainly due to increase in sales of beauty products. High disposable income, and availability of large product portfolio are stimulating the overall market remuneration.

Request Sample copy of this Report @ https://www.marketstudyreport.com/request-a-sample/2963796/

Elaborating form outlook

Global herbal medicine market, as per form type, is segmented into powders, tablets & capsules, syrups, extracts, and others. Among these, extract segment is expected to witness high gains during the forecast period, owing to its utilization in manufacturing several products. Herbs & plants extracts vary from alcoholic extracts, hot water extracts to long-term boiled extracts, and acetic acid extracts depending on the solvent.

Considering source type

As per the report, whole plant sourced herbal medicine market segment is gaining substantial traction due to product’s ability to cure various diseases. As per National Center for Biotechnology Information, about 70% to 80% of the population worldwide preferred traditional drugs for treatment.

Notably, traditional medications are extracted from roots & barks, leaves, fruits, flowers, stalk, and cloves of the plant. For instance, chamomile, a flower, is used as sedative and anxiolytic for relaxation and anxiety. It also reduces swelling and inflammation while aiding in wound healing.  

Analyzing distribution channel

Worldwide herbal medicine market share from e-commerce segment is projected to grow momentously during the forecast period, owing to rising awareness regarding traditional medication, high penetration of mobile phones with internet facilities, and easy accessibility in small towns & villages. Further, rising geriatric population, and cost efficiency of

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Ayurvedic Herbal Medicine – A Natural Method to Healing

The name Ayurveda begins from two Indian words: ayur, which means life, and Veda meaning learning or science. In a wide sense it implies learning concerning the upkeep of life. Ayurveda medicine is a natural way of healing different diseases in the most potent manner. Its effects are visible for a prolonged period.

Ayurveda evolved from the antiquated intelligence of healers, prophets and Rishis that lived somewhere down in the Himalayas. Their knowledge was passed down orally from educator to understudy, and in the end recorded just in the most recent 5,000 years in Sanskrit and named the Vedas. Ayurvedic Herbal Medicine has been refined by a large number of years of functional application and experience. In around 800 BC the main restorative mending school was established in India.

THE TRIDOSHA Hypothesis- THE THREE ESSENTIAL ENERGIES

The three doshas are Vata, Pitta and Kapha. They speak to our hereditary outline and form how we react, both mentally and physically to our surroundings. The established sort, Vata is a blend of Air and Ether. Pitta is the blend of Flame and Water; Kapha – Water and Earth. These components are the establishment of all life.

A comprehension of tridosha framework helps us know a man's sacred inclination, helping the botanist in making a remedial home grown program that coordinates all parts of such individual's reality. The standards and qualities that take after are what a botanists searches for in deciding an individual's constitution.

Vata: oversees all development, breath and the sensory system. Its qualities are depicted as being dry, icy, light, versatile, inconspicuous, unpleasant, hard, whimsical, scattering and clear.

In a disturbed condition it will bring about coldness, dryness, tremors, stomach expansion, obstruction, shortcoming, sleep deprivation and various other neurological protests, and absence of stamina.

Herbs that lessen abundance Vata are nutritive tonics, demulcent with a lovely sweet, salty and acrid taste and warming qualities. Herbs that irritate Vata are sharp, astringent and impactful.

Pitta: represents all changing procedures, digestion system, every single substance response, absorption and course. Its qualities are portrayed as hot, sharp, liquid, light, slick, delicate, and versatile.

In an unhinged condition it will bring about an embittered appearance or a yellowish tone to the skin, eyes, pee and dung. This might be joined by expanded yearning and dryness, smoldering side effect and aggravations.

Herbs that decrease abundance Pitta are drying and cooling, with sharp, astringent and sweet flavors. Herbs that disturb Pitta have a warm sodden nature with impactful, sharp or salty tastes.

Kapha: oversees all attachment, liquidation, development, body steadiness and quality. Its properties are icy, wet, substantial, moderate, dull, smooth, and overcast.

In a disturbed condition it will bring about a reduction of stomach related capacity, over the top mucus and bodily fluid, largeness of the body, coldness, and an awesome longing for rest.

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Herbal Medicine Sicklepod Will Help With Colon Cleansing

Sicklepod and Chinese Senna are both the common names for Senna obtusifolia. Senna is a large species of plant that is prominently found in tropical areas. For many years, the Sicklepod plant has been well known in both the world of herbs and folk medicine. They often act as a laxative and help treat constipation. Much like rhubarb and aloe, the Senna plant has active ingredients in it that give it the ability to loosen stool. It can also help with colon cleansing, as it can cause an increase in the peristaltic movements of the colon when it irritates the mucosa.

Sicklepod leaves have been used for ages in creating tea, and over the years they have developed a lot of medical claims as to what they can do. For a long time it has been a prominent ingredient in a number of tonics and herbal medicines. It has also been a lot in so called “dieter’s teas”. Since it has the properties of a laxative, in addition to acting like a stimulant, it can help someone on a diet to lose weight. In addition to its laxative properties, Senna has also been used to treat various skin diseases when applied directly to the skin in the form of a paste.

Sicklepod is very rich in fiber, which is a powerful ingredient in making sure that bowels move regularly and timely through the body. As for it being a good colon cleanser, during the day to day consumption of food, as waste forms from what the body did not use, it begins to move through the intestines. As the bowels are moving it creates a slimy concoction that gets stuck on the intestinal walls. Things like Senna that are high in fiber are good at removing that slimy residue out of there.

Although Sicklepod has beneficial properties working as a laxative, it needs to be taken in moderate doses. It should never be taken for more than 10 days in a row. Overusing Senna can cause someone to lose fluids, cause their potassium to drop, as well as cause diarrhea. All of that can lead to dehydration, which could eventually cause harm to the muscles as well as the heart. Senna should also not be used during the first trimester when pregnant. Those who suffer from Crohn’s disease, appendicitis, have intestinal obstructions, ulcerative colitis and general abdominal pain should not use any Senna products, tea or otherwise, at all.

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Advantages Of Herbal Medicine Over Conventional Medicine

Herbs are making their mark, many of us believe in the power of herbs and their benefits for health and wellbeing. Modern medicine has not been so keen to look at herbal medicine and prefer to prescribe manufactured medications that are clinically researched and trialled.

Organic herbal remedies are making their presence felt nevertheless, even though modern medicine does not acknowledge it or give it any credence. Of course we can agree that modern medicine has been very effective in the prevention and treatment of many diseases. There are so many ailments and conditions that were fatal hundreds of years ago and can now be treated with modern medicine. This has helps increase the life span of many individuals today.

So many of us opt for herbal remedies and although new laws and regulations are often passed to regress the growth of herbal medicine there are those of us who stull choose to treat themselves using natural and complementary remedies.

Disadvantage Of Modern Medicine
However there is a side of modern medicine that also must a acknowledged and this is that these medicines are made in labs using synthetic ingredients and often there are side effects to contend with. Some side effects can be quite harsh while some may be milder. These negative side effects are the price to pay, while with herbal medicine there is much less chance of this happening if at all. There have been cases where in modern medicine the side effects supersede the actual benefits of the drug and can be quite dangerous. Herbal supplements medicine works on a more holistic level or targeting the cause and treating perhaps more mildly but over long term use has shown to offer good results for many.

Statistics in the USA reveal that one of the other disadvantages of modern medicine is that many patients often experience complications die to various medicines and these can often lead to death. The other disadvantage is the price tag, for most people in the developing world the price of these medicines would be unaffordable. Millions of people cannot afford medical treatment and therefore often lose their lives as they are unable to seek treatment.

One of the most debilitating facts about modern medicine over herbal medicine is that that it emphasizes the cure rather than prevention. This has led to the pharmaceutical industry become a multi-billion dollar market where profits become more important than anything else. Herbal and alternative medicine believes in prevention and treating the cause rather than the symptoms.

While herbal supplements seem to become popular, even the beauty industry is steering that way. These days many brands are looking into herbs as their ingredients for their ethical beauty products and skin care products . Even hair care has gone herbal with so many many brands offering natural hair care products.

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Triphala: A Wonderful Herbal Medicine

In Sanskrit, Tri means three, while phala means fruits. Thus, Triphala is a concoction made from 3 fruits. This herbal concoction has been used in Ayurveda for thousands of years.

Triphala has been used in Ayurveda for treating many different types of ailments, right from dental cavities to digestive issues. It is a prime example of polyherbal medicines since Ayurveda believes that a synergistic effect of different herbs could show a better effect that individual effect of one drug.

Triphala is comprised of powdered fruits /extracts of 3 fruits – Amalaki (Emblica officinalis), Haritaki (Terminalia chebula) and Bibhitaki (Terminalia belerica).

These 3 fruits are detailed below.

a) Amalaki (Emblica officinalis):

The fruits of this tree are widely known as Indian gooseberry or Amla. This fruit is a treasure house and has many benefits –

  • It is one of Ayurveda’s greatest rejuvenators
  • Acts as a strong natural anti-oxidant
  • Helps lower cholesterol
  • Is a great source of Vitamin C
  • Is very helpful in controlling the blood glucose levels in the diabetic patient
  • Helps boost the immune system and metabolism
  • Improves the skin and increases hair growth
  • It improves the vision
  • It balances Pitta

b) Haritaki (Terminalia chebula):

Commonly known as Harada, this herb is also called the Tibetan “king of medicine.” Some of the benefits of this fruits are:

  • It improves cognitive functions,
  • aids in digestion,
  • promotes weight loss
  • It is very helpful in treating an enlarged spleen or liver
  • helps in controlling diabetes
  • Has anti-inflammatory and antioxidant effects
  • Is used as a laxative
  • It significantly calms the Vata dosha

c) Bibhitaki (Terminalia belerica):

It is commonly known as Baheda and displays the following benefits:

  • The fruits of this plant have rejuvenating properties
  • The powder of this fruit helps in curing many respiratory ailments
  • Helps in hepatitis, piles, diarrhea, asthma, dyspepsia, etc.
  • Detoxify the blood, muscles, and fatty tissues
  • It improves vision and hair growth
  • A paste made from this powder and water is applied to the painful or swollen parts of the body to ease the pain
  • Balance Kapha

When these fruits are combined to prepare Triphala, they show the following benefits:

  1. Stimulates digestion
  2. Relieves acidity in the stomach and heals ulcers and gastritis.
  3. Acts as the laxative
  4. Lowers blood cholesterol
  5. Reduces high blood pressure
  6. Helps treat anemia, palpitations, arrhythmia
  7. Helps balance high blood sugar levels in diabetic patients
  8. Heals the side effects of chemotherapy and radiotherapy treatments in cancer
  9. Widely used to treat eye diseases including conjunctivitis, progressive myopia, early stages of glaucoma and cataracts.

To conclude, it is advisable to consume 1 tbsp of this powder with warm water before going to bed for at least one month.

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