An Unexpected Finding on What Might Drive Joint Disease | Health News

By Steven Reinberg, HealthDay Reporter


FRIDAY, Oct. 23, 2020 (HealthDay News) — High levels of a protein that lubricates the knee joint may actually be a harbinger of impending joint disease, a surprising animal study suggests.

The researchers looked at the role of the protein, known as lubricin, in anterior cruciate ligament (ACL) injuries in dogs because it may also be involved in similar injuries in humans.

“Lubricin is crucial for normal joint function and the lubrication of cartilage,” said researcher Heidi Reesink, an assistant professor in equine health at the College of Veterinary Medicine at Cornell University. “We know that if a person or animal doesn’t make that protein, they will develop devastating joint disease affecting all the major weight-bearing joints.”

But Reesink found that in dogs that suffered a ligament tear in the knee, lubricin levels increased within the joint, which is the opposite of the conventional assumptions. “The dogma in this field has been that lubricin decreases in joint disease,” Reesink said in a university news release.

The researchers found that in three dogs, lubricin increased in the time between the initial injury but before any signs of arthritis.

“This indicates that the presence of increased lubricin might actually be a biomarker for predicting future osteoarthritis,” Reesink said. “We also saw increased lubricin in dogs months to years after they injured their ACLs, suggesting that lubricin might be an indicator of ongoing joint instability.

“In looking at horses and dogs, we’re seeing the same pattern,” Reesink said. “The strongest piece of data would be to show it in humans as well.” However, findings in animal studies don’t always translate to humans.

Increased lubricin could become a signal for doctors to intervene or try a different treatment, she added.

The study was published recently in the journal Scientific Reports.

Copyright © 2020 HealthDay. All rights reserved.

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Study Finding Patients of Female Surgeons Fare Better is Removed

An Elsevier journal has, for the moment, removed a paper which found that the patients of female surgeons fare better than those treated by men.

Although the journal didn’t provide an explanation for the move — unfortunately not unusual for Elsevier — a spokesman for the publisher told us that reader complaints about the methodology and statistics in the article prompted the action.

The paper, which appeared last month in Surgery — the official journal of the Society of University Surgeons, Central Surgical Association Central Surgical Association, and the American Association of Endocrine Surgeons — was written by a group at the University of South Florida, in Tampa, led by Tara M. Barry, a general surgery resident at the institution.

“Battle of the sexes: The effect of surgeon gender on postoperative in-hospital mortality,” isn’t available on the journal website. However, a conference abstract by the authors states:

Patients who underwent bariatric procedures, mastectomy and open cholecystectomy had lower rates of in-hospital mortality if the surgeon was female while male surgeons did not have a significant mortality advantage for any of the 25 procedures. Further studies examining national data may provide additional insight regarding the effect of surgeon gender on patient outcomes.

According to the notice, which Elsevier styles a “temporary removal”:

The publisher regrets that this article has been temporarily removed. A replacement will appear as soon as possible in which the reason for the removal of the article will be specified, or the article will be reinstated.

The paper — isn’t the first to find the gender effect in surgery — drew a bit of attention on social media. Most mentions simply called attention to the article. But one surgeon, Olga Muldoon, raised questions about the work:


We emailed Barry for comment but have not heard back.

Elsevier’s Andrew Davis told us:

It appears that, soon after the paper appeared online, the journal has received a complaint regarding the methodology and the statistics included in the paper. The Editors-in-Chief have decided to temporarily remove the Article-in-Press until the investigation is completed.


When the investigation will be finished, the AiP will be either reinstated on Science Direct or permanently withdrawn.

This article originally appeared on Retraction Watch.

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Finding a Dentist With an Effective Checklist

Factors to be Considered While Finding a Dentist

Finding a dentist is something most people dread to even consider. Remember, the little kid who had to be forced to visit a dentist in the popular animation movie, Finding Nemo.

Finding a dentist becomes essential when you:
Have postponed your dental checkup for several years.
Shifted to a new locality.
Feel unsatisfied with your current dentist.
Develop a dental problem when your dentist is not in town.
Become aware that people around you flinch or turn away when you smile or talk to them.

Finding a Dentist: Factors to Consider
Finding a dentist is not difficult but finding the right dentist is. A long term relationship based on trust is what people long to accomplish with their dentists.

The first step to finding a dentist is to take out a list of all dentists available in the locality. Check for references from those you trust or know and then decide.

A simple checklist is provided below to help you arrive at the right decision and not dread visiting your dentist any longer.

1.Where was the dentist educated and trained?
2.Does your dentist have specialization in a specific field?
3.Does your dentist attend conferences and education workshops to stay updated about new developments in the field?
1.Is the dentist's clinic close to your home or office?
2.Is the location of the clinic suitable?
1.Does the dentist have a gentle and caring demeanor?
2.Is the attitude of the dentist and the staff congenial?
3.Is the dentist's approach preventive or curative?

Work Ethics
1.Does the dentist [] offer information on fees and payment plans at the beginning itself?
2.What is the dentist's policy on missed appointments?
3.Are you offered an affordable dental health plan?
1.Is dentist's clinic clean or unkempt?
2.Are the equipments sterilized several times?
3.Does the dentist and his / her staff wear gloves and other protective gear during treatment?
Emergency Care
1.What arrangements are made to handle emergencies outside office hours?
2.Is it possible to contact the dentist in case of an emergency?
3.Are your calls entertained if they are outside the established time?

You can look for licensed dentists in your preferred locality by searching on online directories such as Patient FYI. At Patient FYI, a comprehensive list of dentists across the US is easy to find and merely a click away. Better still, you can request quotes from highly qualified dentists and secure an appointment with them.

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Finding Enough Time For Fitness

Finding time to exercise is one of the biggest problems women face when it comes to fitness. With the busy schedule that most of women juggle today, it's not easy to squeeze in a regular exercise routine. Women have become accustomed to working outside the home while still improving much of the duties at home. Now more than ever, women need some personal time to themselves.

As well as needing time for exercise, women need to have some "me" time to reflect on their spiritual and mental health too. Strive to give yourself at least one hour out of each day for meditation, affirmations and exercise. This will help to strengthen your spirit, mind and body.

With as little as 30 minutes a day of exercise, most women can maintain their weight and keep their bodies in shape. However, if you want to lose weight or train for the next fitness level, you might want to spend a little more time working out. Also, remember to add weights to any workout that starts to become to easy to do. Weights help to add resistance, which builds muscle and helps to burn fat.

Remember, more muscle means more fat burned. A person with more muscle mass will burn fat longer than a person who has less muscle. Muscle continues to burn fat even when the body is at rest. That's why the more your exercise and build muscle, the more calories you can consume. It's not just a matter of consuming calories and burning them off but rather the body's ability to function under peak conditions.

Now that Daylight Savings Time is upon us, use that extra daylight time to get outside and enjoy some fresh air. It's a great time to get in some outdoor aerobics like golf, jogging, skating and of course swimming. If you have children, go outside and actually play with them. A family bike ride will benefit all who join in and will help the young ones catch the fitness fever early on.

The important thing is sticking to an exercise program and staying committed to a fitness regimen. Once fitness becomes a regular part of a person's life, it no longer becomes a challenge to find the time for exercise, it just becomes part of a daily routine.

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Tips on Finding a Good Family Dentist

Are there many dental professionals in your locality? If you and your family have just moved to a new community and you are still familiarizing yourself with the surroundings, it is bit challenging to find a good family dentist. To help you with this task, here are some practical tips:

Ask your old dentist.

Contact you old dentist and see if he or she can recommend some dentists in your new area. Usually, dentists belong to associations and they have connections throughout the country. Your old dentist may have the right family dentist who can take over his or her duty of caring for your family’s oral health.

Ask your new neighbours or co-workers.

New neighbours or co-workers would be much willing to help you. Inquire about their family dentist, the cost of their services, and the quality of their service. Keep in mind the experience they share about a particular dentist. You would know if that clinic is reliable or not based on the stories that previous clients share. Recommendations from people you trust will never fail you.

Search online.

Using the right keywords, you can conduct your search online. Dental clinics especially the long established ones have their own website. You can check a lot of information here and see for yourself if the service appeals to you. Take time to browse about their service, treatment prices, client testimonials or feedback, location, financing of there are any, and most importantly the team of dentists they have. Compare dental offices if there are a lot of results that showed up from your search query. You may be able to find a good clinic near your place. This means convenience on your part.

Check out community forums.

Forums are good place to check as well. Members can recommend the dentists they know and they even share their experience with them. You will read honest reviews and comments if they had been a previous client of a certain clinic. From there you can get ideas which dentist to choose.

It would take you a while to get used to your new environment and build a good relationship with your new dentist. A good start would be to give your dentist a clearer snapshot of your dental and overall health status. Make him or her aware of the current state of your health. Discuss if you have any health condition. Keep in mind that optimal oral health comes as a result of a good partnership between you and your dentist.

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A Few Simple Tips For Finding A Great Dentist

Finding a great dentist isn’t easy. Whether you live in Hawaii or Wichita, this can be a daunting task, especially if you haven’t been to a dentist for a while. But look no further, than this article. Finding a dentist is easier than you think if you simply apply the tips that follow.

Ask People You Know

A great way to find a dentist is to ask other people that you know and trust. Ask your family, colleagues or friends. Often they will have good recommendations. In addition to asking what dentist they recommend, ask about other qualitative factors. Find out if the dentist is friendly, has a nice waiting room and has a great staff.

What if you are new to an area?

If you are new to an area, you may not know anyone who can recommend a great dentist. So what do you do in this scenario? Ask credible people who are in a position to know who the best dentists are. Often hospitals and other health facilities employ the services of a number of dentists. So they are in a great position to know who the best dentists are. All you need to do is call them up and ask for a recommendation.

You can also ask a local dental school. Dental schools are in a great position to know who the best dentists are in the area. In addition, dental schools may even offer lower rates than a regular dentist for dental care. Sure, you will have students performing your dental care, but they will be well supervised by extremely experience dentists who know what they are doing.

Use the Internet

Now days, everything is on the web. Search for a website that lists dentists in your area along with patient reviews. Look for a dentist that is convenient for you and also look at their reviews. Make sure that their patients have a lot of good things to say about them. And if a dentist has a lot of negative reviews, look elsewhere.

Also visit the dentist’s website. You can learn a lot by checking out their website. Does the dentist offer all of the dental services required to meet their needs? You can also get a feel for the dentist’s personality by the way they have designed their site and what they talk about on their website. And if the dentist has posted a video, then you are really in luck. You can get a good sense of their personality too.

Special Dental Needs

When choosing a dentist, you should also consider your special dental needs. If you have healthy teeth, choosing a dentist is easier as all dentists are able to do the basics like cleanings and taking x-rays. But if you have crooked teeth you may want a dentist that specializes in orthodontics. Or if you want your teeth to look better you may want a dentist that specializes in cosmetic dentistry and so on.

Check Your Dental Plan

Another great …

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Why The Dentist In Finding Nemo Is Not a Villain

When watching the famous and family friendly film Finding Nemo, you may not have paid much attention to P. Sherman the dentist who provided his office as the fish tank home. This is a mistake, because without him and his office, the movie could have never played out in the way it did, and Nemo would have never found his way home. While traditionally considered a villain, P. Sherman is actually shown as a caring pet owner, loving uncle and an accomplished dentist.

In the earlier part of the film, the fish plot an escape plan for when P. Sherman cleans their filthy tank. When P. Sherman sees the terrible state of the fish tank, he makes sure, before seeing any patients, to address the issue and give the fish a sparkling clean tank. The AquaScum 3000 is the latest in fish tank cleaning technology and provides regular pH and temperature checks. Of course this thwarts any plans the fish had made for escape, but it demonstrates P. Sherman’s dedication to the care of his office pets. If fish had teeth, it wouldn’t be a far stretch to think he’d take excellent care of them too.

Most importantly, P. Sherman (with his tools and spit fountain) provides the only way for Nemo’s eventual escape back to the ocean, through the pipes. In the rising action of the film, Nemo plays dead in order to get flushed down the toilet, but it ends up being the spit fountain that he is flushed down as a method to escape. No other profession would offer Nemo this route of escape, which makes dentistry key in this film.

Not only does his office provide a safe and comfortable environment for the fish, they are also gaining a valuable education in watching him practice. In the start of the film the fish remark on an in-progress root canal and display their knowledge of the tools as they discuss. There’s no doubt that any dentist student would jump at such a marvelous chance to observe a true professional at work and absorb so much information about the practice.

Though it’s tough to see without pausing and zooming in certain screen shots, P. Sherman has been awarded a number of awards and certificates. These include, The Toothless Grin of the Society of Denture Wearers, a diploma from the Pixar School of Dentistry and the Gums Most Likely to Recede Award. It’s clear that he’s no hack and takes his work very seriously.

A loving uncle, reputable dental professional and great pet owner, P. Sherman is definitely not any sort of villain. In an animated world designed for kids, it’s important to display the adult characters with strong moral values and positive attitudes. Finding Nemo does this in spades and might even convince some kids to not be so afraid of the dentist in the future. If this film has taught us one thing, it’s that dentists aren’t so bad.

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