Tag: chest

 

Biodesix Announces Data from Three Studies on Lung Nodule Diagnosis and Management to be Shared at CHEST Annual Meeting 2020

Research Evaluates Risk Classification for Patients with Lung Nodules

Biodesix, Inc. a leading data-driven diagnostic solutions company with a focus in lung disease, recently published data from three clinical studies, which found important new information on diagnosis and management of lung nodules. Data from these studies, which are being presented at the American College of Chest Physicians (CHEST) annual meeting, demonstrate the value of the Nodify Lung™ testing strategy and confirm previously reported performance of the Nodify XL2® and Nodify CDT™ tests.

Abstract #A1464/Poster #P1319: Identification of Likely Malignant Indeterminate Pulmonary Nodules by Analysis of Autoantibodies Against Lung Cancer-Associated Antigens
Authors: Kevin Doubleday, James Jett, Laura Peek, Trevor Pitcher
A retrospective analysis of the PANOPTIC study found that the blood-based Nodify CDT test accurately identified patients whose lung nodules were likely malignant, which confirms previously reported test performance. Patients identified as Nodify CDT positive may benefit from a more rapid evaluation and intervention for cancer.

Abstract #A1468/Poster #P1325: Lung Nodule Integrated Classifier Biomarker: First Data with Real-World Clinical Use
Authors: James Jett, Kerstin Pohl, Gerard Silvestri, Steven Springmeyer
A real-world clinical use study demonstrates the utility of the blood-based Nodify XL2 test for identifying patients with likely benign lung nodules by integrating the patients’ blood-based protein data with clinical risk factors, resulting in a large proportion of low to moderate risk nodules being reclassified as very low risk. Risk reclassification can reduce invasive procedures on benign nodules and ultimately lead to improved nodule management.

Abstract #A1476/Poster #P1324: Use of Two Blood-Based Biomarker Tests in Series to Reclassify Risk of Indeterminate Pulmonary Nodules
Authors: Kevin Doubleday, James Jett, Laura Peek, Trevor Pitcher, Steven Springmeyer
Data suggest that while standard risk assessment for lung cancer is imprecise, it can be improved with the blood-based Nodify Lung testing strategy. By combining the Nodify CDT and Nodify XL2 tests, patients can be more appropriately assessed for risk of malignancy to help reduce unnecessary procedures on patients with benign nodules and delays in treatment for patients with cancer.

About Biodesix
Biodesix is a leading diagnostic company with a focus in lung disease. The Company develops diagnostic tests addressing important clinical questions by combining multi-omics through the power of artificial intelligence. Biodesix is the first company to offer six non-invasive tests for patients with diseases of the lung. Biodesix launched the SARS-CoV-2 ddPCR™ test and the Platelia SARS-CoV-2 Total Ab in response to the global pandemic and virus that impacts the lung and causes COVID-19. The blood-based Biodesix Lung Reflex® strategy for lung cancer patients integrates the GeneStrat® and VeriStrat® tests to support treatment decisions with results in 72 hours, expediting time to treatment. The blood-based Nodify Lung™ nodule risk assessment testing strategy, consisting of the Nodify XL2™ and the Nodify CDT™ tests, evaluates the risk of malignancy in incidental pulmonary nodules, enabling physicians to better triage patients to the most appropriate course of action. Biodesix also collaborates with many of the world’s leading biotechnology and pharmaceutical companies to solve complex diagnostic challenges

Paramedic returns to work after being knifed in the chest

A paramedic who was knifed in the chest during a 999 call has returned to work after making an incredible recovery.

Deena Evans, 39, was attacked alongside her colleague while treating a patient in Wolverhampton on July 6.

At the time, shocking pictures showed her being treated by colleagues before she was rushed to hospital for treatment to injuries including a chest wound and nerve damage.

But three months on, the paramedic has returned to work after making an amazing recovery and was pictured at her first shift back on Friday (October 16).

Deena Evans
Deena Evans (left), was brutally knifed in the chest while on a 999 emergency call in Wolverhampton on July 6. (SWNS)

West Midlands Ambulance Service shared a picture of her smiling standing next to an ambulance, writing: “We spy a familiar face. Today was her first day back on the road since the incident, she had crew mate Charlie looking after her.”

Evans, who starred in TV show Inside the Ambulance, said: “My recovery is going well. I’m still receiving physio and counselling but it’s helping. I still have numbness in my arm but it so far hasn’t affected my job.

Read more: Horror crash claims fourth victim after teen dies in hospital days later

“My first day I was really nervous, I felt sick and felt like I couldn’t breathe but all the staff helped me, and my crew mate always makes me laugh so it was a good shift.

“The public support has been phenomenal, it really has been overwhelming. It certainly brings back faith in humanity, and I’m glad to be back doing my job.”

Evans and her colleague Michael Hipgrave, 51, were both attacked after they were called to check on the welfare of a man.

Neighbours described hearing “blood curdling screams” and the ambulance workers shouting “please help, he’s got a knife” during the incident.

Hipgrave was discharged from hospital later the same evening after suffering a back injury, while Evans spent another two days receiving treatment.

She has previously told how she was left haunted by the incident, describing how she relives it every time she closes her eyes.

She said: “You just can’t get it out your head and it’s getting over that stage, being able to put it to bed, and at the minute, I don’t think I’m there.

“We’ve had support from the Trust, we’ve got things in place to deal with what happened.

“There’s not enough thank you’s in the world for everybody for the well wishes.”

Hipgrave also told how the incident had taken its toll on his family and friends.

Martyn Smith,